Say you're using our free NFL picks and are betting on a -200 favorite, you need to lay $200 to profit $100, and you would collect $300. If you are looking to play the favorite on the moneyline, the number you see is the number that you need to lay in order to win $100. Conversely, betting on an underdog on the moneyline will earn a larger profit.
Since there is no point spread involved, betting on the favorite requires you to bet more to win a desired amount on the moneyline. Betting on the moneyline means you're just picking the winner of the game.